Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9303135252006Drug Delivery Systems in Pharmaceutical Biotechnology IElective116
Level of Course Unit
Second Cycle
Objectives of the Course
The students are aimed to gain the importance of the delivery systems compatible with the chemical and physical properties of the DNA molecules in the current aplications of gene therapy.
Name of Lecturer(s)
Prof. Dr.Gülten Kantarcı
Learning Outcomes
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
To give information and explain the importance of particular and vesicular systems, pharmaceutical formulations, chemical and mechanic devices, interactive polymers and cationic lipids for delivering of DNA molecules to target cells for non-viral somatic gene therapy.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction
2Microcapsule systems and their properties for loading of nucleic acid and proteins
3Microsphere sytems; polymers used for this sytems and their preperation methods
4Microsphere sytems and nucleic acid and protein loading to this systems
5Characterization of nanoparticular systems and nucleic acid loading to this systems
6Preperation and characterization of nucleic acid and protein loaded solid lipid nanoparticles
7Discussion with research papers about the above subjects
8First exam
9Preperation and characterization of nucleic acid and protein loaded emulsions
10Preperation and characterization of nucleic acid and protein loaded multiple emulsions
11Preperation and characterization of nucleic acid and protein loaded liposomes
12Preperation and characterization of nucleic acid and protein loaded niosomes
13Application ways of particular systems
14Application ways of vesicular systems
15Discussion with research papers about the above subjects
16Final Exam
Recommended or Required Reading
1. Klegerman M.E., Groves M.J., Pharmaceutical Biotechnology Fundamentals and Essentials, 1992. 2. Biotechnology and Pharmacy / editors, Pezzuto J.M., Johnson M.E., Manasse H.R., 1993. 3. Glick B.R., Pasternak J.J., Molecular Biotechnology Principles and Applications, 1994.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Attending Lectures14342
Self Study236
Individual Study for Mid term Examination166
Individual Study for Final Examination11010
Reading14456
TOTAL WORKLOAD (hours)120
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr