Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9303135342016Therapeutic ProteinsElective116
Level of Course Unit
Second Cycle
Objectives of the Course
Understanding structure, design and biological targets of therapeutic proteins manufactured by biotechnological methods and learning recent therapeutic approaches.
Name of Lecturer(s)
Dr. Öğr. Üyesi Bilge Debeleç Bütüner
Learning Outcomes
11. Understanding basic approaches and recent applications used in the design of therapeutic proteins.
22. Using the knowledge of potential therapeutic targets related to signal transduction pathways in developing pharmaceutical formulations.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
Recommended Optional Programme Components
Course Contents
Structural features of therapeutic proteins Immun system Therapeutic targets related to immune system Immunogenicity of therapeutic proteins Structure of monoclonal antibodies Therapeutic applications with monoclonal antibodies Discussion with research papers about the subjects above First Exam Monoclonal antibodies in cancer therapy Monoclonal antibodies in organ transplantation Monoclonal antibodies in inflammatory disease Growth factors, hormones, enzymes and their therapeutic applications Interferon, interleukin and therapeutic applications Discussion with research papers about the subjects above Discussion with research papers about the subjects above Final exam
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Structural features of therapeutic proteinsLecture
2Immun system and Therapeutic targets related to immune systemLecture
3Immunogenicity of therapeutic proteinsLecture
4Stability ty of therapeutic proteinsLecture
5Discussion with research papers about the subjects aboveDiscussion
6Structure of monoclonal antibodies Lecture
7Therapeutic applications with monoclonal antibodiesLecture
8Discussion with research papers about the subjects aboveDiscussion
9First Exam
10Monoclonal antibodies in cancer therapyStudent Presentation/ Lecture
11Monoclonal antibodies in organ transplantationStudent Presentation/ Lecture
12Monoclonal antibodies in inflammatory diseaseStudent Presentation/ Lecture
13Growth factors, hormones, enzymes and their therapeutic applicationsStudent Presentation/ Lecture
14 Interferon, interleukin and therapeutic applicationsStudent Presentation/ Lecture
15Discussion with research papers about the subjects aboveDiscussion
16Final exam
Recommended or Required Reading
1. Pharmaceutical Biotechnology, Fundamentals and Applications, Daan J.A. Crommelin, Robert D. Sindelar, Bernd Meibohm, Springer, ISBN:978-1-4614-6485-3. 2. Pharmaceutical Biotechnology, Concepts and Applications, Gary Walsh, Wiley, ISBN: 978-0-470-01244-4. 3. Kuby Immunology, Thomas J. Kindt (Author), Barbara A. Osborne (Author), Richard A. Goldsby (Author), ISBN-13: 978-1429202114.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures14342
Report Presentation14040
Self Study14040
Individual Study for Mid term Examination12424
Individual Study for Final Examination13636
Homework14684
TOTAL WORKLOAD (hours)270
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
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3
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4
PO
5
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6
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7
PO
8
PO
9
PO
10
PO
11
PO
12
LO1            
LO2            
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr