Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9105045362000Laboratory Techniques for Nuclear Analyses IIElective124
Level of Course Unit
Second Cycle
Objectives of the Course
The objective of this course is to supply the multi-disciplinary students with the basic concepts of radiation, the principles of working with radioactive materials, knowledge of the measurement and analysis techniques and skills in the nuclear field, and analytical considering.
Name of Lecturer(s)
Mahmoud A. A. ASLANİ, Ceren KÜTAHYALI, Müslüm Murat SAÇ, Fazilet Zümrüt BİBER MÜFTÜLER
Learning Outcomes
1Be able to assemble the relationship between radioactivity and modern analytic methods.
2Be able to comprehend the basic concepts and principles of nuclear analytical methods.
3Be able to work with radioactive materials.
4 Be able to observe the new developments in the field of health and natural sciences.
5 Be able to observe the studies in nuclear field.
6 Be able to use the nuclear techniques in order to contribute to human health and prosperity.
7 Be able to use radiation measurement and systems.
8 Be able to study in the field of labeling of new molecules with radionuclide and design radiopharmaceuticals.
9 Be able to gain applicable abilities of nuclear techniques in the field of natural sciences and engineering.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
The basic and fundamental concepts of radiation and measurement systems. The regulations of working with radioactive materials. Unites of radioactivity. Identification of radioactive raw materials. The physical and chemical processes applied on the uranium and thorium ores. Basic principles of UV-Visible spectrophotometer. The laser fluorimetric uranium analyzer. Gamma spectrometer. The basics of alpha and beta counters. Radioactive analysis of environmental samples. The nuclear fuel cycle and waste management. Basic principles of ICP-OES, Surface Area Analyzer and microwave digestion. Novel Radiolabeled molecules and design of radiopharmaceuticals, Radiolabeling, Techniques of Radiolabeling, Techniques of labeling with I-131, Quality control studies using chromatographic methods (High Performance Liquid Chromatography (HPLC), High Performance Liquid Radio Chromatography (HPLRC), Thin Layer Liquid Chromatography (TLC), Thin Layer Liquid Radio Chromatography (TLRC), paper Electrophoresis), Stability constant calculations using potentiometric method, cell culture studies. Continuous radiation detection systems and the working principles, Portable radon detectors and radon measurements in soil with lucas cells, sample preparation by using luminescence technique in dating studies, determination of Po-210 and Pb-210 by using electro deposition method in environmental samples and determination of uranium, thorium and potassium by using spectroscopic methods in the soils.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1The regulations of working with radioactive materials. Units. Thorium ore, crushing, sieving, and leaching process.Assisted laboratory work
2Chemical and radiochemical separation techniques of thorium. Sorption, solvent extraction, ion Exchange, precipitation.Assisted laboratory work
3Measurement of thorium using UV-Visible spectrophotometer in aqueous solutions. Demonstration of laser fluorimetric uranium analyzer. Presentation of gamma spectroscopy.Assisted laboratory work
4The principles of using alpha counter in radioactivity analysis of environmental samples.Assisted laboratory work
5Nuclear fuel cycle, leaching of thorium by microwave digestion equipment.Assisted laboratory work
6The principles of working with ICP-OES for analysis of thorium, the analysis of thorium leaching solution.Assisted laboratory work
7Classification of nuclear waste, nuclear waste management.Assisted laboratory work
8Midterm Exam
9Applications of High Performance Liquid Chromatography (HPLC) ve High Performance Liquid Radio Chromatography (HPLRC).Assisted laboratory work
10Techniques of Labeling with I-131, quality control studies of labeling compounds with I-131 using chromatographic methods.Assisted laboratory work
11Stability constant calculations using potentiometric method, (Proton-ligand and metal-ligand stability constants of Thorium and Cerium complexes.Assisted laboratory work
12Cell Culture and its basic equipments.Assisted laboratory work
13Continuous radiation detection systems and the working principles.Assisted laboratory work
14Portable radon detectors and radon measurements in soil with lucas cells, sample preparation by using luminescence technique in dating studies.Assisted laboratory work
15Determination of Po-210 and Pb-210 by using electro deposition method in environmental samples and determination of uranium, thorium and potassium by using spectroscopic methods in the soils.Assisted laboratory work
16Final Exam
Recommended or Required Reading
1.Benedict M., Pigford T. H., Levi H. W., Nuclear Chemical Engineering, Second Edition, McGraw-Hill Book Company, 1981. 2.Friendlander G., Kennedy J. W., Macias E. S., Miller J. M., Nuclear and Radiochemistry, 3rd Ed., John Wiley and Sons, 1981 3.Gregg,S.J., Sing K.S.W. , Adsorption, Surface Area and Porosity, Academic Press, 1982. 4.Theobald, A.E., Radiopharmaceuticals using radioactive compounds in pharmaceutics and medicine, Ellis Horwood Limited, 1989. 5. Ünak P., Radyofarmasötikler, 2002. 6. Tsoulfanidis, N, Measurement and Detection of Radiation, Hemisephere Publishing Corp., 1983. 7.Yener, G. “Nükleer Radyasyon Fiziği Ders Notları I, 2003. 8. Cothern, C., Smith, J. E., Environmental Radon. Environmental Science Research, Volume 35, A Division of Plenum Publishing Corporation 233 Spring Street, Newyork, N.Y., 1987. 9. National Research Council,. Comparative Dosimetry of Radon in Mines and Homes. Washington D.C. ,1991. 10. Nokaman, E., Radyoaktif Hammaddeler Jeolojisi. Maden Tetkik ve Arama Enstitüsü Yayınları, Eğitim Serisi No:20, Ankara, 1979.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures14114
Team/Group Work14228
Report Presentation14114
Individual Study for Mid term Examination11010
Individual Study for Final Examination11515
Homework12020
TOTAL WORKLOAD (hours)105
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
LO1    5545  5
LO2  5 5 544  
LO3  4 55 45 5
LO4    55    5
LO5  5 555   5
LO6  555555555
LO7  555555455
LO8  555 5    
LO9           
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr