Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
200001052001MEDICAL BIOLOGY AND GENETICSCompulsory115
Level of Course Unit
First Cycle and Second Cycle
Objectives of the Course
To get them informed about cell division, hereditary materials, human genetics, cancer genetics, methods and applications for analysing genetic diseases
Name of Lecturer(s)
Prof. Dr. Nejat Topçuoğlu, Assoc. Prof. Dr. Cumhur Gündüz, Assoc. Prof. Dr. Zuhal Eroğlu, Ydr. Assoc. Prof. Dr. Buket Kosova
Learning Outcomes
1Get informed about the mutual effects of genes and to calculate the divergence of Mendel’s relations
2Define and list basic chromosomal abnormalities and mutation types
3Define and confront otosomal and gonosomal inheritance patterns
4Get informed about and illustrate methods for analysing genetic diseases
5Define a cell and its basic characteristics
6Explain cell division types and stages
7Define the similarities and differences between genomic and mitochondrial DNA, get informed about the basic principles of inheritance
8Get informed about anormal cell differentiation and to define cancer development mechanisms
9Get informed about basic genetics and to explain Mendel’s Laws
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Structure of the genetic material, cell division, cancer development mechanisms, Mendel’s Laws in inheritance, mutation types, way to inherit chromosomal abnormalities and methods for analysing genetic diseases
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction to Biology Medical. Related Sciences, the cell definition, history Types of light and electron microscopy
2The primitive and genuine nucleus cells, the general properties of the cell. Viruses and bacteria
3Cell synthesizes and uses organic and inorganic compounds. Structure of nucleic acids
4Functional structures of nucleus, nucleolus and chromosomes
5Molecular structure of the cell membrane and cell membrane differentiations. Cytoplasmic organelles, function of the endoplasmic reticulum
6Ribosomes, Golgi complex, mitochondria, Lysosomes
7Mitochondria, Lysosomes
8Sentriol, Mikrotubililer and Cilia
9Cell division
10Structure and properties of membrane receptors
11Molecular basis of intercellular interactions
12Abnormal cell differentiation, mechanisms of cancer cells
13Mid-term exam
14Structure of Genetic Material 1-Light Microscopy: Structure, function Structures of plant and animal cells a) the onion skin cells b) intra-oral mucosal epithelium
15DNA Replication, Transcription, Translation "Cellular elements of blood Human blood-the blood of the Frog Blood smear technique and the preparation"
16Mitochondrial Genome DNA isolation
17General Genetics, Mendel's Laws "Protozoa, Paramecium"
18Reciprocal Effects of Genes and Mendelian Ratios Deviation Mitosis
19"Polygenic inheritance in living organisms and Multiple alleles, linkage and crossing over." Meiosis
20Basic Chromosome Abnormalities "Human Genetics (sex chromatin) Human Metaphase chromosomes"
21Mutations, Mutagens and teratogens
22"Human Genetics. Medical Genetics developmental characteristics, genetic disease relationship. Mendel's principles of human genetics initiative"
23"Human Genetics. Medical Genetics X-linked inheritance a) Recessive b) Dominant Y-chromosome inheritance Multifactorial-polygenic inheritance"
24"Review of genetic diseases Methods. Genetic counseling (prevention of genetic diseases)"
25Single Gene Disorders and DNA Diagnosis
26Evaluation
27Final exam
Recommended or Required Reading
TEXT BOOK: 1. Tıbbi Genetik, Prof.Dr. Nurettin Başaran, 8. Baskı, Yayın Yılı: 2003, Nobel Tıp Kitapevi 2.Tıbbi Biyoloji Ders Notları, Prof.Dr. Ayşe Başaran, 7. Baskı, Yayın Yılı: 2009, Pelikan Yayınları CONTRIBUTIVE BOOKS: 1.Moleküler Hücre Biyolojisi, Prof.Dr. Hasan Veysi Güneş, 2. Baskı, Yayın Yılı: 2006, Kaan Kitapevi
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination290
Laboratory Examination110
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination111
Attending Lectures264104
Practice20240
Individual Study for Mid term Examination122
Individual Study for Final Examination122
TOTAL WORKLOAD (hours)150
Contribution of Learning Outcomes to Programme Outcomes
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr