Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
300002412006BIOCHEMISTRY ICompulsory234
Level of Course Unit
First Cycle and Second Cycle
Objectives of the Course
The aim of this course is to give main notions about the biological energy providing the basis and sustainability of cellular functions, enzymatic systems, structural and functional properties of biomolecules and their metabolisms in order to understand how the biological systems works.
Name of Lecturer(s)
Prof. Dr.Aysun Pabuççuoğlu, Prof.Dr. Ayfer Yalçın, Prof. Dr.Sibel Konyalıoğlu, Prof. Dr.Petek Ballar, Doç. Dr. Güliz Armağan
Learning Outcomes
1Being able to have knowledge on the main biochemical pathways and mechanisms related to catabolism of macromolecules composing metabolic energy.
2Being able to associate the metabolism with the biochemical pathways functioning in lipid catabolism
3Being able to associate the metabolism with the biochemical pathways functioning in protein catabolism
4Being able to have the principle notions about the importance and cellular functions of antioxidant systems and compounds
5Being able to have the knowledge on biochemical components of the cell and the biological importance of the water
6Being able to comprehend the knowledge on structure-function relationship of proteins and their biological importance
7Being able to have the knowledge on structure-function relationship of carbonhydrates and their biological importance
8Being able to have the knowledge on structure-function relationship of lipids and their biological importance.
9Being able to have main notion on characteristics of the enzymes, enzyme kinetics and catalysis mechanisms.
10Being able to interpret the physiological functions of vitamines and coenzymes in metabolism process by understanding their importance
11Being able to corralate biochemical pathways functioning on the existence and storage of metabolic energy.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Introduction, History of Biochemistry, The Chemical Components of Cell and water,Amino acids as the constituents of proteins, The 3-dimentional structures, features and functions of proteins, Enzymatic catalysis and kinetics, Carbohydrates: Definition, main structures, classification, D/L isomers of monosaccharides, biologically important monosaccharides and their derivatives, Lipids: Definition, main structures, classification, fatty acids, triacylglycerols, phospholipids, micells, steroids and cholesterol, Functions of coenzymes and cofactors, Lipid soluble vitamins and their physiological functions, Bioenergetics, Formation and storage of metabolic energy, Glycolysis pathway, Citrate cycle, Oxidative phosphorylation, Radicals and free oxygen radicals, antioxidant systems and compounds, Apoptosis, Pentose phosphate pathway and glutathione, Glycogen degradation, Glyconeogenesis, Fatty acid degradation, synthesis of ketone bodies,Amino acid degradation and urea cycle
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction, History of Biochemistry, The Chemical Components of Cell and Water
2Amino acids as the constituents of proteins, the 3-dimentional structures, features and functions of proteins
3Enzymatic catalysis and kinetics
4Enzymatic catalysis and kinetics
5Carbohydrates: Definition, main structures, classification, D/L isomers of monosaccharides, biologically important monosaccharides and their derivatives.
6Lipids: Definition, main structures, classification, fatty acids, triacyglycerols, phospholipids, micells, steroids and cholesterol
7Functions of coenzymes and cofactors.
8Lipid soluble vitamins and their physiological functions.
9Bioenergetics, Formation and storage of metabolic energy, Glycolysis pathway
10Citrate cycle
11Oxidative phosphorylation
12Radicals and free oxygen radicals, antioxidant systems and compounds
13Pentose phosphate pathway and glutathione.
14Glycogen degradation , Glyconeogenesis
15Fatty acid degradation, synthesis of keton bodies
16Amino acid degradation and urea cycle
Recommended or Required Reading
Lecture notes are supplied by the lecturer
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Sınavı1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination111
Attending Lectures16348
Self Study339
Individual Study for Mid term Examination12525
Individual Study for Final Examination14040
Reading6212
Performance339
TOTAL WORKLOAD (hours)145
Contribution of Learning Outcomes to Programme Outcomes
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1
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LO1 3                   
LO2 3                   
LO3 4                   
LO4 5                   
LO5 5                   
LO6 5                   
LO7 5                   
LO8 5                   
LO9 5                   
LO10 5                   
LO11 5                   
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr