Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
300003422007PHARMACOGNOSY IICompulsory365
Level of Course Unit
First Cycle and Second Cycle
Objectives of the Course
The aim of Pharmacognosy II course is to provide students to be able to identify fixed oils of pharmaceutical importance and be able to list drugs and medicinal uses of fixed oils of biological origin. In addition it is aimed to make students be capable of defining the structures of glycosides and be able to comprehend and identify the general structures and general properties of cyanogenetic, anthronoid, flavonoid, simple phenol, lignan, coumarin, iridoid and glucosinolates, sulpfur compounds, lectins and tannins that are important in terms of pharmacy and be able to identify the drugs and active constituents and establish relationship between structures and their effects on human health.
Name of Lecturer(s)
Prof. Dr. Bijen KIVÇAK, Prof. Dr. Nehir SOMER, Prof. Dr. Hüsniye KAYALAR, Prof. Dr. G. İrem KAYA, Doç. Dr. Buket BOZKURT, Doç. Dr. Tuğçe FAFAL
Learning Outcomes
1To be able to explain the general features and quality control methods of fixed oils
2To be able to identify drugs of fixed oils and be able to set relations between effects and pharmaceutical use of fixed oils
3To be able to identify general structures of glycosides and be able to give examples of these type of compounds ( cyanogenetic, anthranoid, flavonoid, simple phenol, lignan, coumarin, iridoid and senevol glycosides) and to be able to gain knowledge about the chemical structures of active compounds, be able to distinguish them from each other and with various characteristics of these compounds be able to establish a relationship between the active compounds and various effects on human health
4By listing the general properties of sulfur compounds, lectins and tannins, be able to identify the drugs containing these components and be able to explain their pharmacetical uses
5To be able to analyse and define transverse sections of radix, cortex, folia, fructus and semen parts of plants and by the help of anatomical knowledge gained by Pharmacognosy I practices, be able to microscobically identify the unknown drug powders.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
General features of fixed oils,Principles of purity and quality control of fixed oils, fixed oil drugs and their importance in terms of pharmacy,general glycoside structures, natural sources of glycosides, herbal drugs and pharmaceutical importance of cyanogenetic glycosides, anthronoid , flavonoid glycosides, simple phenol heterosides, lignan and coumarin glycosides, iridoid glycosides, glucosinolates and sulfur compounds, betalains, sweetener proteins and lectins.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Fixed Oil *Definition *Physicfal Properties *Principles of purity and quality conrol methodsMicroscobical analysis on transverse sections and powdered drugs of radix (roots)parts of plant materials
2Drugs and pharmaceutical importance of fixed oils *Oleum Olivae *Oleum Sesami *Oleum Arachidis *Oleum Amygdalae *Oleum PapaverisMicroscobical analysis on transverse sections and powdered drugs of leaf (folia) parts of plant materials
3Drugs and pharmaceutical importance of fixed oils (cont..) *Oleum Ricini *Oleum Chaulmoograe *Oleum Lini *Oleum Cacao *Oleum Iecoris aselli Structures and drug souces of waxes *Cera flava *Cera alba *Cera Carnauba Cetaceum Adeps Lanae anhydricusMicroscobical analysis on transverse sections and powdered drugs of semen parts of plant materials
4General Structures and sources of Glycosides *O-glycosides *N-glycosides *C-glycosides *S-glycosides Pharmaceutical importance of Cynanogenetic glycosides and their sources of drugs *Folia Laurocerasi *Semen Amydalae amaraeMicroscobical analysis on transverse sections and powdered drugs of fructus parts of plant materials
5Pharmaceutical importance of Anthronoid glycosides and their sources of drugs *Rhizoma Rhei *Cortex Frangulae *Cortex Rhamni purshianae *Fructus Rhamni catharticae *Fol,a Sennae *Fructus Cassia fistulaeMicroscobical analysis on transverse sections and powdered drugs of stem-cortex parts of plant materials
6Pharmaceutical importance of Anthronoid glycosides and their sources of drugs (cont..) *Aloe *Araroba *Herba Hyperici *Radix Rubiae *CoccinellaPrinciples of general microscobical examination and identification of unknown powdered drugs.
7Structures of Flavonoids *Flavonoids and flavonols *Chalcone, dihydrochalcone and aurones *İsoflavonoids *Anthocyanidol *Proanthocyanidol *Neoflavonoids Flavonoid glycosides and pharmacetical importance of drugs as sources of flavonoid glycosides *Fructus Petroselini *Herba Rutae *Herba Capsella bursa-pastoris *Folia Betulae *Flos CrataegiMicroscobical identification of 3 packages of unknown drug powder
8Flavonoid glycosides and pharmacetical importance of drugs as sources of flavonoid glycosides (cont...) *Lespedeza capitata *Cortex Viburni *Flos Sambuci *Herba Violae tricoloris *Ginkgo biloba *Semen Cardui mariae *Flos Helychrysi *Radix Ononidis *Folia/Fructus Myrtilli *Flores CarthamiMicroscobical identification of 3 packages of unknown drug powder
9Midterm examMidterm exam
10Simple Phenol Heterosides and sources of drugs *Fructus Vanillae *Cortex Salicis *Populi Gemmae *Folia Uvae ursi *Flores Spiraeae ulmariae *Summitates Solidago virgae Lignan Compounds, pharmaceutical importance and biological sources and activity of lignans *Resina Podophylli, pahramaceut,ical uses of podophyllotoxin and its semi synthetic derivatives *Fructus Silybum mariae *Semen Schizandrae chinensis *Radix Eleutherococci Coumarin Compounds and pharmacetical importance of drugs as sources of coumarins *Cortex Fraxini Herba Meliloti Cortex GnidiMicroscobical identification of 3 packages of unknown drug powder
11General properties of Iridoid glycosides and pharmacetical importance of drugs as sources of iridoid glycosides *Flos Verbasci *Herba Monotropea *Galium species *Plantago species *Radix Valerianae (Valepotriates) *Folia Menyanthis *Radix Gentianae *Radix Harpogophyti procumbens *Folium OlivarumMicroscobical identification of 3 packages of unknown drug powder
12Glucosinolates and pharmacetical importance of drugs as sources of glucosinolates *Semen Sinapis nigrae, Semen sinapis albae *Raphanus sativus Pharmacetical importance of drugs as sources of sulfur compounds *Bulbus Allii sativi *Bulbus Allii cepaeComplementary practices for previous laboratory work
13Pharmacetical importance of drugs as sources of betalains *betacyanin *Betaxanthin Pharmacetical importance of sweetener proteins and sources of drugs *Tomatine *Monellin *Miraculin Effects, toxicity and pharmacetical importance of drugs as sources of lectins *Abrin *Ricin *Herba Visci albiComplementary practices for previous laboratory work
14Structures of Tannins *Catechic tannins *Hydrolyzable tannins Properties of Tannins Determination of Tannins Pharmacetical importance of drugs as sources of tannins *Gallae *Acidum tannicumComplementary practices for previous laboratory work
15Pharmacetical importance of drugs as sources of tannins (cont..) *Valonae *Folia/Cortex Hamamelidis *Radix Ratanhiae *Catechu *Fructus Rosae caninae *Folia Rhois Cariariae *Rhizoma Tormentillae *Cortex Quercus *Herba Alchemillae *Fructus Myrtilli *Folia Theae *Herba AgrimoniaeComplementary practices for previous laboratory work
16Final examFinal exam
Recommended or Required Reading
1. Farmakognozi, Mekin Tanker, Nevin Tanker; Ankara Üniversity Faculty of Pharmacy Publishing No:66- 1 (1991) 2. Bitkisel Drogların Anatomik Yapısı, Asuman Baytop, İstanbul University Faculty of Pharmacy Publishing (1972) 3. Pharmacognosy Phytochemistry Medicinal Plants,2nd Edition; J. Bruneton, 1999 4. Pharmacognosie, Phytopharmazie, 8.Auflage; R. Haensel, O. Sticher 2007 (in German) ISBN-10 3-540-34256-7, ISBN-13 978-3-540-34265-4
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination111
Quiz10.50.5
Attending Lectures14228
Practice14342
Report Preparation14114
Individual Study for Mid term Examination12525
Individual Study for Final Examination13535
Individual Study for Quiz133
TOTAL WORKLOAD (hours)149.5
Contribution of Learning Outcomes to Programme Outcomes
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LO1      423        3   
LO2 4    5454   4   4   
LO3 4    55542  4   4   
LO4 4    55542  4   4   
LO5 3    44343      5   
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr