EGE UNIVERSITY Lifelong Learning Programme

Description of Individual Course Units

Course Unit Code	Course Unit Title	Type of Course Unit	Year of Study	Semester	Number of ECTS Credits
300003422007	PHARMACOGNOSY II	Compulsory	3	6	5

Level of Course Unit

First Cycle and Second Cycle

Objectives of the Course

The aim of Pharmacognosy II course is to provide students to be able to identify fixed oils of pharmaceutical importance and be able to list drugs and medicinal uses of fixed oils of biological origin. In addition it is aimed to make students be capable of defining the structures of glycosides and be able to comprehend and identify the general structures and general properties of cyanogenetic, anthronoid, flavonoid, simple phenol, lignan, coumarin, iridoid and glucosinolates, sulpfur compounds, lectins and tannins that are important in terms of pharmacy and be able to identify the drugs and active constituents and establish relationship between structures and their effects on human health.

Name of Lecturer(s)

Prof. Dr. Bijen KIVÇAK, Prof. Dr. Nehir SOMER, Prof. Dr. Hüsniye KAYALAR, Prof. Dr. G. İrem KAYA, Doç. Dr. Buket BOZKURT, Doç. Dr. Tuğçe FAFAL

Learning Outcomes

1	To be able to explain the general features and quality control methods of fixed oils
2	To be able to identify drugs of fixed oils and be able to set relations between effects and pharmaceutical use of fixed oils
3	To be able to identify general structures of glycosides and be able to give examples of these type of compounds ( cyanogenetic, anthranoid, flavonoid, simple phenol, lignan, coumarin, iridoid and senevol glycosides) and to be able to gain knowledge about the chemical structures of active compounds, be able to distinguish them from each other and with various characteristics of these compounds be able to establish a relationship between the active compounds and various effects on human health
4	By listing the general properties of sulfur compounds, lectins and tannins, be able to identify the drugs containing these components and be able to explain their pharmacetical uses
5	To be able to analyse and define transverse sections of radix, cortex, folia, fructus and semen parts of plants and by the help of anatomical knowledge gained by Pharmacognosy I practices, be able to microscobically identify the unknown drug powders.

Mode of Delivery

Face to Face

Prerequisites and co-requisities

None

Recommended Optional Programme Components

None

Course Contents

General features of fixed oils,Principles of purity and quality control of fixed oils, fixed oil drugs and their importance in terms of pharmacy,general glycoside structures, natural sources of glycosides, herbal drugs and pharmaceutical importance of cyanogenetic glycosides, anthronoid , flavonoid glycosides, simple phenol heterosides, lignan and coumarin glycosides, iridoid glycosides, glucosinolates and sulfur compounds, betalains, sweetener proteins and lectins.

Weekly Detailed Course Contents

Week	Theoretical	Practice	Laboratory
1	Fixed Oil Definition Physicfal Properties *Principles of purity and quality conrol methods	Microscobical analysis on transverse sections and powdered drugs of radix (roots)parts of plant materials
2	Drugs and pharmaceutical importance of fixed oils Oleum Olivae Oleum Sesami Oleum Arachidis Oleum Amygdalae *Oleum Papaveris	Microscobical analysis on transverse sections and powdered drugs of leaf (folia) parts of plant materials
3	Drugs and pharmaceutical importance of fixed oils (cont..) Oleum Ricini Oleum Chaulmoograe Oleum Lini Oleum Cacao Oleum Iecoris aselli Structures and drug souces of waxes Cera flava Cera alba Cera Carnauba Cetaceum Adeps Lanae anhydricus	Microscobical analysis on transverse sections and powdered drugs of semen parts of plant materials
4	General Structures and sources of Glycosides O-glycosides N-glycosides C-glycosides S-glycosides Pharmaceutical importance of Cynanogenetic glycosides and their sources of drugs Folia Laurocerasi Semen Amydalae amarae	Microscobical analysis on transverse sections and powdered drugs of fructus parts of plant materials
5	Pharmaceutical importance of Anthronoid glycosides and their sources of drugs Rhizoma Rhei Cortex Frangulae Cortex Rhamni purshianae Fructus Rhamni catharticae Fol,a Sennae Fructus Cassia fistulae	Microscobical analysis on transverse sections and powdered drugs of stem-cortex parts of plant materials
6	Pharmaceutical importance of Anthronoid glycosides and their sources of drugs (cont..) Aloe Araroba Herba Hyperici Radix Rubiae *Coccinella	Principles of general microscobical examination and identification of unknown powdered drugs.
7	Structures of Flavonoids Flavonoids and flavonols Chalcone, dihydrochalcone and aurones İsoflavonoids Anthocyanidol Proanthocyanidol Neoflavonoids Flavonoid glycosides and pharmacetical importance of drugs as sources of flavonoid glycosides Fructus Petroselini Herba Rutae Herba Capsella bursa-pastoris Folia Betulae *Flos Crataegi	Microscobical identification of 3 packages of unknown drug powder
8	Flavonoid glycosides and pharmacetical importance of drugs as sources of flavonoid glycosides (cont...) Lespedeza capitata Cortex Viburni Flos Sambuci Herba Violae tricoloris Ginkgo biloba Semen Cardui mariae Flos Helychrysi Radix Ononidis Folia/Fructus Myrtilli Flores Carthami	Microscobical identification of 3 packages of unknown drug powder
9	Midterm exam	Midterm exam
10	Simple Phenol Heterosides and sources of drugs Fructus Vanillae Cortex Salicis Populi Gemmae Folia Uvae ursi Flores Spiraeae ulmariae Summitates Solidago virgae Lignan Compounds, pharmaceutical importance and biological sources and activity of lignans Resina Podophylli, pahramaceut,ical uses of podophyllotoxin and its semi synthetic derivatives Fructus Silybum mariae Semen Schizandrae chinensis Radix Eleutherococci Coumarin Compounds and pharmacetical importance of drugs as sources of coumarins *Cortex Fraxini Herba Meliloti Cortex Gnidi	Microscobical identification of 3 packages of unknown drug powder
11	General properties of Iridoid glycosides and pharmacetical importance of drugs as sources of iridoid glycosides Flos Verbasci Herba Monotropea Galium species Plantago species Radix Valerianae (Valepotriates) Folia Menyanthis Radix Gentianae Radix Harpogophyti procumbens *Folium Olivarum	Microscobical identification of 3 packages of unknown drug powder
12	Glucosinolates and pharmacetical importance of drugs as sources of glucosinolates Semen Sinapis nigrae, Semen sinapis albae Raphanus sativus Pharmacetical importance of drugs as sources of sulfur compounds Bulbus Allii sativi Bulbus Allii cepae	Complementary practices for previous laboratory work
13	Pharmacetical importance of drugs as sources of betalains betacyanin Betaxanthin Pharmacetical importance of sweetener proteins and sources of drugs Tomatine Monellin Miraculin Effects, toxicity and pharmacetical importance of drugs as sources of lectins Abrin Ricin Herba Visci albi	Complementary practices for previous laboratory work
14	Structures of Tannins Catechic tannins Hydrolyzable tannins Properties of Tannins Determination of Tannins Pharmacetical importance of drugs as sources of tannins Gallae Acidum tannicum	Complementary practices for previous laboratory work
15	Pharmacetical importance of drugs as sources of tannins (cont..) Valonae Folia/Cortex Hamamelidis Radix Ratanhiae Catechu Fructus Rosae caninae Folia Rhois Cariariae Rhizoma Tormentillae Cortex Quercus Herba Alchemillae Fructus Myrtilli Folia Theae Herba Agrimoniae	Complementary practices for previous laboratory work
16	Final exam	Final exam