Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
300004142002PHARMACEUTICAL BIOTECHNOLOGYCompulsory473
Level of Course Unit
First Cycle and Second Cycle
Objectives of the Course
This course aims to provide essential knowledge for Pharmacy students about the processes such as transferring genetic information from one organism to another for production of pharmaceuticals. The students are aimed to gain the ability of molecular approach in pharmaceutical sciences. The subjects are discussed in relation to pharmaceutical aspects of the human genome project and the students learn basic methods which are applied in the pharmaceutical area as well as commercial and ethical issues of Pharmaceutical Biotechnology.
Name of Lecturer(s)
Prof Dr. Zeki Topçu - Prof. Dr. Gülten Kantarcı- Dr. Ögr. Üyesi Yücel Başpınar, Dr. Öğr. Üyesi Bilge Debeleç Bütüner, Arş. Gör. Dr. Hasan Akbaba, Arş. Gör. Dr. Mustafa Kotmakçı
Learning Outcomes
1Comprehension of basic biotechnology techniques
2Gaining of molecular genetic fundamentals and interpetation.
3Improvement of personal vision on gene engineering and biotechnology applications
4Improving research capabilities on pharmacutical biotechnology.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Recombinant DNA Technology, Molecular Research Procedures, Manipulation of gene expression in prokaryotes, Molecular diagnostics: Immunological diagnostic procedures, Human Somatic Gene therapy: Regulation and patenting pharmaceutical biotechnology.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Restriction endonucleases, VectorsLecture
2Genomic and cDNA libraryLecture
3Genetic transformationLecture
4Agarose, polyacryl amide gel electrophorezisLecture
5DNA sequencing techniquesLecture
6Polymerase chain reactionLecture
7First exam
8Monoclonal antibodiesLecture
9Gene expression from strong and regulatable promotersLecture
10Binding of clonned genes to expressed vectors,Lecture
11Fusion proteins increasing protein stabilityLecture
12Biotechnological vaccines, DNA diagnostic systemsLecture
13Ex vivo/in vivo gene therapyLecture
14Antisense therapyLecture
15Patenting biotechnology inventions, ethical considerationsLecture
16Final exam
Recommended or Required Reading
Glick, B. R. And Pasternak, J. J. ‘Molecular Biotechnology’, ASM Press 1994, Washington D. C.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination144
Attending Lectures143.549
Criticising Paper8324
Reading6212
TOTAL WORKLOAD (hours)91
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
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4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
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13
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14
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15
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16
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17
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18
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19
PO
20
PO
21
LO14    4 5 53    2   13
LO2 3  3 333         1 3
LO34  3   4 4 33113 3  3
LO4  4         4       4
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr