Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
402024012000INDUSTRIAL MICROBIOLOGYCompulsory475
Level of Course Unit
First Cycle
Objectives of the Course
The aim of this course is to get the students acquainted with the description of industrial microbiology and fermentation process, inoculum, stock culture media and industrial fermentation.
Name of Lecturer(s)
Prof. Dr. İhsan YAŞA
Learning Outcomes
1Learning the principal concepts of industrial microbiology
2Learning the fermentor types used for production
3Comprehending the physicochemical processes
4Apprehending the chromotographic and enymatic methods
5Being able to implement the fields of applications of industrial microbiology to current life
6Compreending and implementing the production of enzymes, vitamins, antibiotics, aminoacids and organic acids
7Being able to implement his knowledge of industrial production and share them orally and in written
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
EndüstriyDescription of industrial microbiology, instruments and their usage, fermentation processes, inoculum, fermentation stock culture media, industrial fermentation and increase in the output, organic solvents, organic acids, dextran, amino acids, enzimes, vitamines, growth factors and the obtaining of food stuffs.el Mikrobiyoloji’nin tanımı ve ilgili kavramlar, fermentasyon ekipmanları ve kullanımı,Fermentasyon işlemleri,inokulum,fermentasyon ve stok kültür ortamları, endüstri çapında fermentasyon ve verimin arttırılması,organik çözücüler,organik asitler,dekstran,amino asitler,enzimler,vitaminler, gelişme faktörleri ve besin maddelerinin elde edilmesi.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1The definiton of industrial microbiology and the principal concepts Introduction to Industrial microbiology and general informations
2Fermentors for special use, starting to industrial fermentation, screening methods for microorganisms (Primary screening)Citric acid production – General description
3Secondary screening,determining and testing the fermentation products, the physicochemical processes Citric acid production – Screening for a suitable microorganism and quantitative sugar analysis of the used raw material
4Spectrophotometric methods and chromotographic processes. Citric acid production – Activation and sporulation of the suitable microorganism
5Biological and enzymatic processes Commencing to citric acid production
6The inoculum media, fermentation media and biological environments Assinging the fermentation product and quantitative analysis
7Growth factors, contamination and sterilization of the media, scaling up the fermentation, tandem and multiplex fermentations, continuous fermentations Penicillin production – Introduction and general discription
8Midterm ExamPenicillin production – Screening for a suitable microorganism and screening methods
9The fields of applications of industrial microbiology, etraction of organic solvents, industrial ethanol (ethyl alcohol) production, acetone-butanol fermentation Penicillin production - Activation and sporulation of the suitable microorganism
10Glycerine fermentation, Butandiol fermentationCommencing to penicillin production
11Production of organic acids: Production of tartaric acid, gluconic acid, citric acid and lactic acid The quantitative analysis of the product
12Itaconic acid, kojic acid, ustilagic acid, , malic acid, fumaric acid, oxalic acid and gibberellic acid Rennin production – Introduction and general discription
13Production of Dextrans and amino acids, fermentation of glutamic acid and production of L-lisin Rennin production – Activation and sporulation of the suitable microorganism
14Production of antibiotics (Penicilin, cephalosporin, tetracycline, chlortetracycline, streptomycin, erytromycin and chloramphenicol, production of enymes The quantitative analysis of the product
15Microbial production of vitamins (Vitamin B12, B2, A and C), production of Biogas Laboratory Exam
16Final ExamLab Exam
Recommended or Required Reading
Brock T.D., ‘Biology of Microorganisms’ Chapter 30. Industrial Microbiology. Pearson Education Inc. London (2003) Brock T.D. ‘Mikroorganizmaların Biyolojisi’ Bölüm 30. Çeviri Editörü Cumhur Çökmüş, Palme yayıncılık, Ankara, (2010)
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination175
Project Presentation110
Laboratory Examination115
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures14228
Practice339
Laboratory14228
Report Preparation224
Report Presentation224
Self Study6212
Individual Study for Mid term Examination11313
Individual Study for Final Examination11313
Reading11333
Report212
TOTAL WORKLOAD (hours)150
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
PO
14
LO1         3    
LO2 4            
LO3 4            
LO4  54   4 4 4  
LO5    4    4    
LO6         4   5
LO7              
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr