Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
402024012000INDUSTRIAL MICROBIOLOGYCompulsory475
Level of Course Unit
First Cycle
Objectives of the Course
The aim of this course is to get the students acquainted with the description of industrial microbiology and fermentation process, inoculum, stock culture media and industrial fermentation.
Name of Lecturer(s)
Prof. Dr. İhsan YAŞA
Learning Outcomes
11. Learning the principal concepts of industrial microbiology
22. Learning the fermentor types used for production
33. Comprehending the physicochemical processes
44. Apprehending the chromotographic and enymatic methods
55. Being able to implement the fields of applications of industrial microbiology to current life
66. Compreending and implementing the production of enzymes, vitamins, antibiotics, aminoacids and organic acids
77. Being able to implement his knowledge of industrial production and share them orally and in written
Mode of Delivery
Face to Face
Prerequisites and co-requisities
Recommended Optional Programme Components
none
Course Contents
Description of industrial microbiology, instruments and their usage, fermentation processes, inoculum, fermentation stock culture media, industrial fermentation and increase in the output, organic solvents, organic acids, dextran, amino acids, enzimes, vitamines, growth factors and the obtaining of food stuffs.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
11 The definiton of industrial microbiology and the principal concepts Introduction to Industrial microbiology and general informations
22 Fermentors for special use, starting to industrial fermentation, screening methods for microorganisms (Primary screening)Citric acid production – General description
33 Secondary screening,determining and testing the fermentation products, the physicochemical processes Citric acid production – Screening for a suitable microorganism and quantitative sugar analysis of the used raw material
44 Spectrophotometric methods and chromotographic processes. Citric acid production – Activation and sporulation of the suitable microorganism
55 Biological and enzymatic processes Commencing to citric acid production
66 The inoculum media, fermentation media and biological environmentsAssinging the fermentation product and quantitative analysis
77 Growth factors, contamination and sterilization of the media, scaling up the fermentation, tandem and multiplex fermentations, continuous fermentations Penicillin production – Introduction and general discription
88 Midterm Penicillin production – Screening for a suitable microorganism and screening methods
99 The fields of applications of industrial microbiology, etraction of organic solvents, industrial ethanol (ethyl alcohol) production, acetone-butanol fermentation Penicillin production - Activation and sporulation of the suitable microorganism
1010 Glycerine fermentation, Butandiol fermentationCommencing to penicillin production
1111 Production of organic acids: Production of tartaric acid, gluconic acid, citric acid and lactic acid The quantitative analysis of the product
1212 Itaconic acid, kojic acid, ustilagic acid, , malic acid, fumaric acid, oxalic acid and gibberellic acid Rennin production – Introduction and general discription
1313 Production of Dextrans and amino acids, fermentation of glutamic acid and production of L-lisin Rennin production – Activation and sporulation of the suitable microorganism
1414 Production of antibiotics (Penicilin, cephalosporin, tetracycline, chlortetracycline, streptomycin, erytromycin and chloramphenicol, production of enymes The quantitative analysis of the product
1515 Microbial production of vitamins (Vitamin B12, B2, A and C), production of Biogas Laboratory Exam
1616 Final Exam
Recommended or Required Reading
COURSE BOOK: Brock, T. D., “Biology of Microorganisms” Chapter 30. Industrial Microbiology. Pearson Education Inc. London (2003). Brock T.D. ‘Mikroorganizmaların Biyolojisi’ Bölüm 30. Çeviri Editörü Cumhur Çökmüş, Palme yayıncılık, Ankara, (2010).
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination175
Project Presentation110
Laboratory Examination115
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Turkish
Work Placement(s)
none
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Attending Lectures14228
Laboratory14228
Report Presentation224
Project Preparation339
Project Presentation224
Reading11333
Homework428
TOTAL WORKLOAD (hours)114
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
PO
14
LO1   5     5    
LO2 4            
LO3 4            
LO4  4 4    5    
LO5         4 5  
LO6   4     4  5 
LO7              
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr