Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
10420201E11370GENETICS IICompulsory365
Level of Course Unit
First Cycle
Objectives of the Course
The aim of this course is to give the student an understanding of the molecular mechanisms of the basic concepts of genetics; the ability to have analytical thinking on genetics; the ability to relate and synthesize the concepts of genetics and other disciplines; an understanding of the role of genetics in biological structure, function and organization.
Name of Lecturer(s)
Assoc. Prof. Dr. N.Ülkü KARABAY YAVAŞOĞLU
Learning Outcomes
1To be able to learn the basic concepts of genetics in molecular level
2To be able to relate and synthesize the concepts of genetics
3To be able to examine the relationship between the concepts and experiments of genetics
4To be able to relate analytical thinking, experimental logic, quantitative analysis and problem solving
5To be able to relate the approaches of different disciplines such as molecular biology, biochemistry, statistics with genetics
6To be able to understand and relate the role of genetics in biological structure, function and organization.
7To be able to understand daily life applications of the consepts of genetics
8To be able to search genetics databases and evaluate informations from multiple sources and viewpoints by means of oral and written manners
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Chromosome structure and organisation of DNA , Gene mutations and repair mechanisms, DNA recombination:homolog recombination, DNA recombination:site specific recombination, transposition, V(D)J recombination, Control of gene expression in Prokaryotes, Control of gene expression in Eukaryotes, Developmental genetics, Genetics and Cancer, Quantitative genetics, Population genetics, Genetics and Evolution, Genomics and Proteomics, Model organisms, Genetics and ethics
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Chromosome structure and organisation of DNA DNA staining in bacteria and yeast
2Gene mutations and repair mechanisms Methods for determination of genotoxic potential of chemicals, Comet assay
3DNA recombination:homolog recombination Mutation test in Serratia Problem solving
4DNA recombination:site specific recombination, transposition, V(D)J recombination UV lethality and mutations in yeasts
5Control of gene expression in Prokaryotes UV damage repair in Yeasts, fotoreactivation
6Control of gene expression in Eukaryotes DNA isolation from plant material
7Developmental genetics: cell-cell interactions in developmental process, programmed cell death Laboratory exam
8Midterm Polymerase chain reaction (PCR)
9Genetics and Cancer: Cell cycle control, tumor supressor genes, oncogenes Agarose gel electrophoresis
10Quantitative genetics DNA isolation from human and animal blood cells
11Population genetics Stem Cell technologies and IVF methods
12Genetics and Evolution Polygenic inheritance (problem solving)
13Genomics and Proteomics Population genetics (problem solving)
14Model organisms Laboratory exam
15Genetics and ethicsLaboratuar Sınavı
16Final Exam
Recommended or Required Reading
TEXT BOOK Klug,W.S., Cummings, M.R. and Spencer, C.A. “Genetik Kavramlar” Ç ed. Öner, C ve ark. Palme Yayıncılık, Ankara, 2009. OTHER REFERENCES A Bozcuk, A. Genetic. Palme Publishers, 2000 Tamarın,R. “Principles of Genetics”, Thirt Edition. Wm. C. Brown Publishers, 1991. Stansfield W.D., “Theory and Problems of Genetics”, Sc.edit.Schaum’s Outline Series,McGraw-Hill Book Compaany,New York, 1998.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
English
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures15230
Laboratory15230
Problem Solving339
Report Preparation236
Report Presentation224
Self Study6212
Individual Study for Homework Problems236
Individual Study for Mid term Examination11212
Individual Study for Final Examination11212
Reading11222
TOTAL WORKLOAD (hours)147
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
PO
14
LO1 11      1  1 
LO2  1 1       1 
LO3111         1 
LO4 1  1       1 
LO5  1         1 
LO6        1111 1
LO7   1 11       
LO8              
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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