Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
404003932012BASIC BIOCHEMISTRYCompulsory353
Level of Course Unit
First Cycle
Objectives of the Course
The aim of this introduction course of biochemistry is to explain the structural chemistry of the components of living matter and the relationship of the biological function to chemical structure, the chemistry of processes and substances that store and transmit biological information.
Name of Lecturer(s)
Assoc. Prof. Dr. Funda Kartal, Research Assistant Dr. Güliz Ak
Learning Outcomes
1Understand the chemical principles of biochemical reactions.
2Understand the structures and chemistry of proteins, carbohydrates, lipids and nucleic acids.
3Understand the principles of anabolic and catabolic metabolism.
4Be able to understand the connection between metabolic pathways
5Be able to use basic biochemistry knowledge in other disciplines.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Amino acids,peptides, proteins, enzymes, coenzymes, nucleic acids, protein biosynthesis, biochemical evolution, DNA replication, transcription and translation, protein metabolism, oxidative decarboxylation and crebs cycle, basic carbohydrates, polysaccharides, isoprenoid lipids, steroids and caratenoids, fats and metabolisms, phospholipids, glycolipids, lipoproteins, biological membranes, energy store in membranes, respiration chain, photosynthesis, nutrition, minerals and vitamins.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction to biochemistry. Development of biochemistry.
2Amino acids and primer structure of proteins. Ionization of amino acids, peptide bond. Primer structure analysis of proteins.Internet search Reading
3Secondary, tertiary, quaternery structure of proteins. Protein structure-function. Protein purification. Amino acid and protein metabolism.
4Enzymes. Enzyme action mechanism. Enzyme classification. Michaelis-Menten equation. Types of enzyme immobilization. Internet search Reading
5Coenzymes and vitamins
6Nucleic acids. Replication, transcription, translation.Internet search Reading
7Introduction to metabolism. Thermodynamics and metabolism. ATP.
8Midterm exam
9Carbohydrates and glycolysis. Regulation of glycolysis.Internet search Reading
10Citrate cycle, pentose phosphate pathway, gluconeogenesis, glycogen metabolism.
11Lipids and Lipoproteins. Digestion and absorbstion of lipids. Triglyceride synthesis and degradation. Internet search Reading
12Lipid metabolism.
13Electron transport and oxidative phosphorylation. Internet search Reading
14Photosynthesis
15Membrane transport mechanismsInternet search Reading
16Final Exam
Recommended or Required Reading
Course Book(s): David L. Nelson, Michael M. Cox, ”Lehninger Principles of Biochemistry, Worth Publishers, (2000) Helper Book(s): Stryer, “Biochemistry” Worth Publishers, (2002) D.Voet, J.G.Voet, “Biochemistry” Willey,John and Sons, (2003)
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
English
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures14228
Self Study12336
Individual Study for Mid term Examination199
Individual Study for Final Examination11010
Reading717
TOTAL WORKLOAD (hours)94
Contribution of Learning Outcomes to Programme Outcomes
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr