Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
300005912019CHRONOPHARMACOKINETICS AND THERAPEUTIC DRUG MONITORINGElective593
Level of Course Unit
First Cycle and Second Cycle
Language of Instruction
Turkish
Objectives of the Course
To have information about chronopharmacokinetic and therapeutic drug monitoring.
Name of Lecturer(s)
Prof. Dr. Ercüment Karasulu, Doç. Dr. Emel Öykü Çetin Uyanıkgil
Learning Outcomes
1To have information about chronopharmacokinetics
2To have information about diseases and circadian rhythm
3To have information about the factors affecting the circadian rhythm
4To have knowledge about chronopharmacodynamic studies and drugs
5To have information about therapeutic drug monitoring
6To have knowledge about Preanalytical Variables and Therapeutic Drug Tracking
7To have information about the measurement of therapeutic drug concentrations with analytical techniques in biological fluids
8To have information about commonly monitored drug classes
Mode of Delivery
Face to Face
Prerequisites and co-requisities
none
Recommended Optional Programme Components
none
Course Contents
Chronopharmacokinetics Diseases and sircadien rhythm Factors affecting the circadian rhythm Chronopharmacıdynamic studies and drugs Overview of Therapeutic Drug Monitoring Preanalytical Variables and Therapeutic Drug Monitoring Analytical Techniques for Measuring Concentrations of Therapeutic Drugs in Biological Fluids Classes of drugs commonly monitored
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction to chronopharmacokineticsnonenone
2Chronopharmacokinetics, chronobiology, chronopharmacologynonenone
3Hastalıklar ve sirkadyen ritmnonenone
4Chronopharmacodynamic studies and drugsnonenone
5Chronopharmacodynamic studies and drugsnonenone
6Chronopharmacodynamic studies of cardiovascular drugsnonenone
7Chronopharmacodynamic studies of respiratory drugsnonenone
8Chronopharmacodynamic studies of endocrinological and gastrointestinal system drugsnonenone
9Chronopharmacodynamic studies of central nervous system drugsnonenone
10Midtermnonenone
11Overview of Therapeutic Drug Monitoringnonenone
12Preanalytical Variables and Therapeutic Drug Monitoringnonenone
13Analytical Techniques for Measuring Concentrations of Therapeutic Drugs in Biological Fluidsnonenone
14Classes of drugs commonly monitorednonenone
15Classes of drugs commonly monitorednonenone
16Final examinationnonenone
Recommended or Required Reading
CHRONOPHARMACEUTICS Science and Technology for Biological Rhythm-Guided Therapy and Prevention of Diseases Chronobiology and Cardiovascular Diseases, An Issue of Heart Failure Clinics, Volume 13-4 Farewell to the Internal Clock A contribution in the field of chronobiology Advances in chromatographic techniques for therapeutic drug monitoring Clinical Challenges in Therapeutic Drug Monitoring Handbook of Drug Monitoring Methods Therapeutics and Drugs of Abuse Analytical Methods For Therapeutic Drug Monitoring And Toxicology
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Work Placement(s)
none
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination111
Attending Lectures11414
Team/Group Work155
Individual Study for Homework Problems11010
Individual Study for Mid term Examination11010
Individual Study for Final Examination12525
Reading11010
TOTAL WORKLOAD (hours)76
Contribution of Learning Outcomes to Programme Outcomes
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr