Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
404004902010INTRODUCTION TO NATURAL PRODUCTS CHEMISTRYElective483
Level of Course Unit
First Cycle
Objectives of the Course
Description of primary and secondary metabolites; Classification of natural products (phenolic compounds, terpenes, alkaloids, etc.); Understanding how to use chromatographic techniques in separation of natural products; Primary investigations of natural products (by using TLC and PC).
Name of Lecturer(s)
Prof. Dr. Özgen ÇALIŞKAN
Learning Outcomes
1How to separate natural products by using chromatographic methods.
2Presentation of isolation procedures for secondary metabolites after their primary identification.
3To have a ability and knowledge for following recent progress in natural product chemistry.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Primary investigation and isolation methods of primary and secondary metabolites, such as alkaloids, terpenes, saponins, flavanoids and other phenolic compounds, anthocyanins etc.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Description of natural products. Classification of primary and secondary metabolites. Functions of secondary metabolites in plants and importance for humans. Genaral chromatographic methods used in isolation and classification of natural products
2Description of natural products. Classification of primary and secondary metabolites. Functions of secondary metabolites in plants and importance for humans. Genaral chromatographic methods used in isolation and classification of natural products
3Alkaloids: Classification, primary investigation by chromatographic methods and isolation procedures.
4Alkaloids: Isolation procedures (continued)
5Terpenes: Structures and classifications, monoterpenes, structures, biological activities, sesquiterpenes and sesquiterpen lactones, structures, classifications, and activities, diterpenes, structures, functions in plants, classifications and activities.
6Triterpenes: common triterpen skeletons, functions in plants, classifications and activities.
7Saponins and classifications, biological activities, tetraterpenes, steroids
8Midterm exam
9Primary investigation of terpenes via chromatographic methods, example chromatograms and spray reagents.
10Phenolic compounds, descriptions, functions in plants, classifications, phenols and phenolic acids: structures, quinones and structures.
11Phenyl propanoids: classification and structures. Coumarines: description, classification, structures, biological importance, lignans, structures and functions in plants.
12Flavanoids: structures, functions in plants, basic skeletons and classifications.
13Antocyanins: structures, primary identification of phenolic compounds and example chromatograms.
14Primary identification of phenolic compounds and example chromatograms (continued).
15Course overview
16Final Exam
Recommended or Required Reading
1. J. Clayden, N. Greeves, S. Warren and P Wothers, "Organic Chemistry", Oxford University Press, 2000. 2. Pengelly, A., The Constituents of Medicinal Plants, CABI, 2004.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures16232
Individual Study for Mid term Examination11818
Individual Study for Final Examination13636
TOTAL WORKLOAD (hours)90
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
PO
14
PO
15
PO
16
PO
17
PO
18
PO
19
PO
20
PO
21
PO
22
LO1    5 55 4            
LO2       5  4      5    
LO3   5       4   4 5    
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr