Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9101036212010Biochemical View of Metal ToxicologyElective118
Level of Course Unit
Third Cycle
Language of Instruction
Turkish
Objectives of the Course
. Actually, most metals have toxic effects even at lowconcentration levels; therefore, they are of great importance fort he environment and human health. This class aims at teaching toxic effects of heavy metals on human health.
Name of Lecturer(s)
Assoc. Prof. Dr. Sinan AKGÖL
Learning Outcomes
1Evaulating research results in heavy metals and heavy metal removal.
2Following contemporary results and making national and international presentations in the concerned area.
3Learning about heavy metals
4Learning about general characteristics and toxic effects of heavy metals.
5Acquiring up to date knowledge of heavy metal toxicology and being able to evaulate it.
6Being informed about heavy metal removal and designing alternative removal methods.
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Elemental composition of the human body. Biologically important elements, roles and amounts. Reasons for exposure to heavy metals. Heavy metal toxicities. Heavy metal toxicity in water. Aluminium and aluminium metabolism, toxic effects and toxicity of aluminium. Arsenic and arsenic metabolism, toxic effects and toxicity of arsenic. Mercury and mercury metabolism, toxic effects and toxicity of mercury. Lead and lead metabolism, toxic effects and toxicity of lead. Iron and iron metabolism, toxic effects and toxicity of iron. Cadmium and cadmium metabolism, toxic effects and toxicity of cadmium. Chromium and chromium metabolism, toxic effects and toxicity of chromium. Antidots which are used in metal poisining. Separation process. Polymeric sorbents. Applications.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Elemental composition of the human body. Biologically important elements, roles and amounts.
2Reasons for exposure to heavy metals. Heavy metal toxicities.
3Heavy metal toxicity in water.
4Aluminium and aluminium metabolism, toxic effects and toxicity of aluminium.
5Arsenic and arsenic metabolism, toxic effects and toxicity of arsenic.
6Midterm
7Mercury and mercury metabolism, toxic effects and toxicity of mercury.
8Lead and lead metabolism, toxic effects and toxicity of lead.
9Iron and iron metabolism, toxic effects and toxicity of iron.
10Cadmium and cadmium metabolism, toxic effects and toxicity of cadmium.
11Chromium and chromium metabolism, toxic effects and toxicity of chromium.
12Antidots which are used in metal poisining.
13Separation process. Polymeric sorbents. Applications.
14Presentation
15Presentation
16Final Exam
Recommended or Required Reading
Casarett and Doull’s “Toxicology, The basic Science of Poisons”, Macmillan Publishing Company, 2nd Edition, New York, 1975. Irena Sherameti, Ajit Varma, “Soil Heavy Metals (Soil Biology)”, Sringer-Verlag, Berlin, 2010. William Rasmussen, Natural Mercury Detoxification (Paperback), Metabolic Balance Press (LLC), Florida, USA, 2002.
Planned Learning Activities and Teaching Methods
Activities are given in detail in the sections of "Assessment Methods and Criteria" and "Workload Calculation".
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Sınavı1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Attending Lectures14342
Project Preparation21020
Project Presentation224
Seminar224
Self Study14570
Individual Study for Homework Problems14456
Individual Study for Mid term Examination12020
Individual Study for Final Examination12525
TOTAL WORKLOAD (hours)245
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
LO14  5   4   5
LO2    5   5 55
LO3    5 4     
LO4    55      
LO5  555  4 5 5
LO6 5 4 5 4   5
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr