Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9103106312014Gene TherapyElective118
Level of Course Unit
Third Cycle
Objectives of the Course
Inform students about recents developments in gene therapy
Name of Lecturer(s)
Prof. Dr. Bahattin TANYOLAÇ
Learning Outcomes
1Therapy with genes in Inherited disease
2Learning new tools for gene therapy
Mode of Delivery
Face to Face
Prerequisites and co-requisities
Molecular Genetics, Molecular Biology, Biochemistry
Recommended Optional Programme Components
None
Course Contents
1. Gene therapy strategy 2. target disease 3. Gene therapy vectors 4. Viruses 5 . Non-viral agent
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Gene therapy strategies Genetic engineering tools
2Target diseaseDNA amplification
3Drug and therapy testMarker application
4Gene therapy vectorsProblem solving
5Viruses in generalFragment cloning
6Adeno virüsler (ADV) ve Adeno-associated virus (AAV)ADV uygulamaları
7Retroviral vectorsLiteratur search
8Exame
9Lentivirus (HIV) vectorsLiteratur search
10Herpes simplex virusCloning fragment in virus
11Non-viral approachesLiteratur search
12RNA-based treatmentsNcbi web site appl.
13Greatest limitations of current technologiesNcbi web site appl.
14Promising gene therapy conceptsNcbi web site appl.
15Human hereditary diseases SCIDNcbi web site appl.
16X-linked disordersLiteratur search
Recommended or Required Reading
Mountain, A. (2000) Gene therapy: the first decade. TIBTECH 18, 119-128. Wu, N. and Ataai, M. M. (2000) Production of viral vectors for gene therapy applications. Current opinion in biotechnology 11, 205-208. Chapter 21 pp. 616-629
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination133
Quiz414
Problem Solving14228
Project Presentation122
Seminar28256
Project Design/Management17171
Report14114
Individual Study for Quiz23060
TOTAL WORKLOAD (hours)240
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
LO15555555555555
LO25555555555555
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Ege University, Bornova - İzmir / TURKEY • Phone: +90 232 311 10 10 • e-mail: intrec@mail.ege.edu.tr