Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
9103106382014Development and production of immunotherapeuticsElective129
Level of Course Unit
Third Cycle
Objectives of the Course
In this course, we aimed to give general and detailed specific information about general principles of development and production of immunotherapeutics and comprehend the importance and future application.
Name of Lecturer(s)
Doç. Dr. Ayşe Nalbantsoy
Learning Outcomes
1Evaluate the fundamental conception information of immunotherapeutics.
2Comprehend the importance and application range of development and production of immunotherapeutics
3To take interest and discuss in new approaches of commercial applications in immunotherapeutics
4Gaining qualification about the issues such as the design of research projects, thesis preparation, and the evaluation of the results by specializing in the areas of development and production of immunotherapeutics
5Being able to read, understand and evaluate scientific articles about immunotherapeutics
6Being able to improve the knowledge and theory by using the data about immunotherapeutics through scientific methods.
7Being able to improve theory for the future immunotherapeutic drug production
Mode of Delivery
Face to Face
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Historical background, introduction to immunotherapeutics, basic terminology, immunotherapeutics drugs and marketing, strategies for development of immunotherapeutics drugs, techniques for immunotherapeutics drugs poduction, large scale production of immunotherapeutics drugs, commercialization, future immunotherapeutics.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Historical background Introduction to immunotherapeutics, basic terminology
2Immunological and immunochemical techniques
3İmmunotherapeutics drugs and marketingDiscussion on developed drug models
4Application of immunotherapeuticsDiscussion on developed drug models
5Progression and development of immunotherapeutics Discussion on developed drug models
6Strategies for development of immunotherapeutics Discussion on developed drug models
7Commercialization of immunotherapeuticsDiscussion on developed drug models
8MidtermExamDiscussion on developed drug models
9Basic principles of production Discussion on developed drug models
10Lab scale productionDiscussion on developed drug models
11Large scale production IDiscussion on developed drug models
12Large scale production IIDiscussion on developed drug models
13Downstream processDiscussion on developed drug models
14Future immunotherapeutics
15Design of new immunotherapeutics
16Final Exam
Recommended or Required Reading
Casale, T., B., Stokes, J. R. 2010. Future Forms of İmmunotherapy, J. Allergy Clin. Immunol. 127(1), 8-15 Gao, J., Bernatchez, C., Sharma, P., Radvanyi, L., G., Hwu, P. 2013. Advances in the Developments of Cancer Immunoterapies, Cell Press, 34 (2), 90-98. Gomase V, Dwivedi S. 2010. Immunobiotechnology, Targets of Life. VDM Verlag, Dr. Müller, Germany. Janeway CA, Travers P, Hunt S, Walport M 1997. Immunobiology: The Immune System in Health and Disease. Garland Publishing Inc., New York, USA. Kuby, 2007. In: Kindt TJ, Goldsby RA, Osborne BA, Kuby J (Eds.), Immunology. Sixth ed. W.H. Freeman and Company, New York. Levy, A., Chargari, C., Cheminant, M., simon, N., Bourgier, C., Deutsch, E. 2013. Radiation Therapy and immunotherapy: implications for combined cancer treatment, critical reviews in oncology/hematology, 85(13), 278-287 Mesenchymal Stem Cells: Methods and Protocols (Methods in Molecular Biology) (Hardcover) by Darwin J. Prockop (Editor), Donald G. Phinney (Editor), Bruce A. Bunnell (Editor), 2008, Humana Press. Process Scale Bioseparatıons For The Biopharmaceutical Industry. Shukla A.A, Etzel M.R., Gadam S (Editors). 2007. Taylor&Francis. Animal Cell Culture: Essential Methods. J.M. Davis (Editor), 2011, John Wiley & Sons. Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells (Hardcover) by Victor A. Vinci (Editor), Sarad R. Parekh (Editor), 2003, Humana Press Inc.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
SUM0
Language of Instruction
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination144
Practice14456
Discussion14456
Question-Answer14456
Brain Storming10330
Project Presentation12020
Seminar12448
TOTAL WORKLOAD (hours)270
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
LO13 54 555435  
LO2 54 3    4 44
LO34 5 43 5 45 5
LO45 443 5 4 4  
LO5 5  5 43  3  
LO65 45 4 53 4 4
LO7  5   4  4 35
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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